Article

CEP290 myosin-tail homology domain is essential for protein confinement between inner and outer segments in photoreceptors

2019-06-05

Abstract excerpt

<h4>ABSTRACT</h4> Mutations in CEP290 cause various ciliopathies involving retinal degeneration. CEP290 proteins localize to the ciliary transition zone and are thought to act as a gatekeeper that controls ciliary protein trafficking. However, precise roles of CEP290 in photoreceptors and pathomechanisms of retinal degeneration in CEP290 -associated ciliopathies are not sufficiently understood. Using Cep290 co...

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Literature Corpus work: 88d3c131-0a35-53ea-b460-b720e1b5d5c5
DOI: 10.1101/660738

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