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Jiao-tai-wan and its effective component-coptisine alleviate cognitive impairment in db/db mice through the JAK2/STAT3 signaling pathway

13 Aug 2024

Abstract excerpt

BACKGROUND: Cognitive impairment (CI) is now well-accepted as a complication and comorbidity of diabetes mellitus (DM), becoming a serious medical and social problem. Jiao-tai-wan (JTW), one of noted traditional Chinese medicine (TCM), showed dual therapeutic effects on DM and CI. Nevertheless, the potential mechanism is unclear. PURPOSE: This study sought to investigate the mechanism how JTW protected against DM...

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PMID: 39178683
DOI: 10.1016/j.phymed.2024.155954

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