Article
Epigenetic mechanisms of plasticity and resistance in glioblastoma: therapeutic targets and implications
2025-05-16
Abstract excerpt
Glioblastoma (GBM), a highly aggressive and malignant form of primary adult brain cancer, poses significant therapeutic challenges. Despite our improved understanding of the cellular and molecular mechanisms underlying tumorigenesis and the evolution of GBM, targeted molecular therapies have failed to improve patient survival outcomes. The failure of standard treatments and targeted therapies is mainly attributed...
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Identifiers and source
- Literature Corpus work
- 79775a00-d66d-567d-80af-062484429c67
- DOI
- 10.3389/freae.2025.1519449