Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuronal and tumourigenic boundaries of glioblastoma plasticity

29 Nov 2022

Abstract excerpt

Glioblastoma (GBM) remains the most lethal primary brain cancer largely due to recurrence of treatment-resistant disease. Current therapies are ultimately ineffective as GBM tumour cells adapt their identity to escape treatment. Recent advances in single-cell epigenetics and transcriptomics highlight heterogeneous cell populations in GBM tumours originating from unique cancerous genetic aberrations. However, they...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glioma Diagnosis and Treatment
Share to Immune cells in cancer
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36460606
DOI: 10.1016/j.trecan.2022.10.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuronal and tumourigenic boundaries of glioblastoma plasticityPMID 36460606Read ↗

Epigenetic mechanisms of plasticity and resistance in glioblastoma: therapeutic targets and implicationsSemantic proximity Read ↗

Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell ResolutionSemantic proximity Read ↗

The Glioblastoma Landscape: Hallmarks of Disease, Therapeutic Resistance, and Treatment OpportunitiesSemantic proximity Read ↗

Emerging Role of Glioma Stem Cells in Mechanisms of Therapy ResistanceSemantic proximity Read ↗

Glioblastoma Heterogeneity and Cancer Cell PlasticitySemantic proximity Read ↗

Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerabilitySemantic proximity Read ↗

Hitting a Moving Target: Glioma Stem Cells Demand New Approaches in Glioblastoma TherapySemantic proximity Read ↗

Cell-Intrinsic and Cell-Extrinsic Therapeutic Targets in Glioblastoma: Overcoming Resistance Through Tumor Microenvironment Modulation and Precision MedicineSemantic proximity Read ↗

Epigenetic pathways and glioblastoma treatmentSemantic proximity Read ↗

A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneitySemantic proximity Read ↗

The Amazing and Deadly Glioma Race.Semantic proximity Read ↗

Spatially Integrated Multi-Omics reveals the Multicellular Landscape of Progenitor-Driven Glioblastoma ProgressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.