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Epigenetic pathways and glioblastoma treatment

23 Jul 2013

Abstract excerpt

Glioblastoma multiforme (GBM) is the most common malignant adult brain tumor. Standard GBM treatment includes maximal safe surgical resection with combination radiotherapy and adjuvant temozolomide (TMZ) chemotherapy. Alarmingly, patient survival at five-years is below 10%. This is in part due to the invasive behavior of the tumor and the resulting inability to resect greater than 98% of some tumors. In fact,...

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Share to Epigenetics and DNA Methylation
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PMID: 23807265
DOI: 10.4161/epi.25440

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