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Article

Epigenetic dysregulation in glioma.

Cancer science - 1 Apr 2014

Kondo Yutaka, Katsushima Keisuke, Ohka Fumiharu, Natsume Atsushi, Shinjo Keiko

Abstract excerpt

Given that treatment options for patients with glioblastoma are limited, much effort has been made to clarify the underlying mechanisms of gliomagenesis. Recent genome-wide genomic and epigenomic analyses have revealed that mutations in epigenetic modifiers occur frequently in gliomas and that dysregulation of epigenetic mechanisms is closely associated with glioma formation. Given that epigenetic changes are...

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Source

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Identifiers

PMID: 24843883
DOI: 10.1111/cas.12379
PMCID: PMC4317798

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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