Article

The association between rs6859 in<i>NECTIN2</i>gene and Alzheimer’s disease is partly mediated by pTau

2024-06-22

Abstract excerpt

<h4>Introduction</h4> Emerging evidence suggests a connection between vulnerability to infections and Alzheimer’s disease (AD). The nectin cell adhesion molecule 2 (NECTIN2) gene coding for a membrane component of adherens junctions is involved in response to infection, and its single nucleotide polymorphism (SNP) rs6859 was significantly associated with AD risk in several human cohorts. It is unclear, however, ho...

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Literature Corpus work: 7965b5fa-ab39-5526-842b-23e75330b6b4
DOI: 10.1101/2024.06.21.24309310

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