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Article

Vaccination Against Pneumonia May Provide Genotype-Specific Protection Against Alzheimer’s Disease

3 Oct 2023

Abstract excerpt

Vaccine repurposing that considers individual genotype may aid personalized prevention of Alzheimer's disease (AD). In this retrospective cohort study, we used Cardiovascular Health Study data to estimate associations of pneumococcal polysaccharide vaccine and flu shots received between ages 65-75 with AD onset at age 75 or older, taking into account rs6859 polymorphism in NECTIN2 gene (AD risk factor)....

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PMID: 37807778
DOI: 10.3233/jad-230088

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