Article

Epigenetic Silencing of TET1 Mediated Hydroxymethylation of Base Excision Repair Pathway During Lung Carcinogenesis

2020-06-04

Abstract excerpt

<title>Abstract</title> <p><bold>Backgroud:</bold> The methylcytosine dioxygenase Ten-eleven translocation 1 (TET1) is an important regulator for the balance of DNA methylation and hydroxymethylation through various pathways. Increasing evidence has suggested that TET1 probably involved in DNA methylation and demethylation dysregulation during chemical carcinogenesis. However, the role and mechanism of TET1 durin...

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Literature Corpus work: 79408273-fd34-5289-ac58-27f00d5e444c
DOI: 10.21203/rs.3.rs-32537/v1

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