Article

Novel insights into <i>I</i> <sub>Kur</sub> modulation by Lgi3-4: Implications in atrial fibrillation

2024-10-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Patients with atrial fibrillation (AF) exhibit a reduction in the ultrarapid outward potassium current ( I Kur ) conducted by K V 1.5 channels. Ion channels are closely modulated by regulatory subunits, forming macromolecular complexes known as channelosomes. One such regulatory family is the leucine-rich glioma-inactivated protein family (Lgi1-4), which has been shown to...

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Literature Corpus work: 7920bffd-118e-5ae2-bbb2-ca078ff0d50b
DOI: 10.1101/2024.10.03.616587

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