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Article

Novel KCNA5 mutation implicates tyrosine kinase signaling in human atrial fibrillation.

Heart rhythm - 1 Sept 2010

Yang Tao, Yang Ping, Roden Dan M, Darbar Dawood

Abstract excerpt

BACKGROUND: Emerging evidence has strongly implicated hereditary determinants for atrial fibrillation (AF). Loss-of-function mutations in KCNA5 encoding the ultrarapid delayed rectifier potassium current I(Kur) have been identified in AF families. OBJECTIVE: The purpose of this study was to determine the clinical and biophysical phenotypes in a KCNA5 mutation with deletion of 11 amino acids in the N-terminus of...

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Source

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Identifiers

PMID: 20638934
DOI: 10.1016/j.hrthm.2010.05.032
PMCID: PMC2932792

Genes

KCNA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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