Article

Cotranslational protein folding can promote the formation of correct folding intermediate

2020-05-10

Abstract excerpt

Cotranslational folding is vital for proteins to form correct structures in vivo. However, it is still unclear how a nascent chain folds at atomic resolution during the translation process. Previously, we have built a model of ribosomal exit tunnel and investigated cotranslational folding of a three-helices protein by using all-atom molecular dynamics simulations. Here we shall study the cotranslational folding of...

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Literature Corpus work: 7900f84d-cc18-5113-a402-cb059b4e904e
DOI: 10.1101/2020.05.08.084228

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