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Article

Folding with downhill behavior and low cooperativity of proteins.

Proteins - 1 Apr 2006

Zuo Guanghong, Wang Jun, Wang Wei

Abstract excerpt

The downhill folding observed experimentally for a small protein BBL is studied using off-lattice Gō-like model. Our simulations show that the downhill folding has low cooperativity and is barrierless, which is consistent with the experimental findings. As an example of comparison in detail, the two-state folding behavior of proteins, for example, protein CI2, is also simulated. By observing the formation of...

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PMID: 16416404
DOI: 10.1002/prot.20857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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