Article
Induction and maintenance of mouse totipotent stem cells by a defined chemical cocktail
2022-06-23
Abstract excerpt
<title>Abstract</title> <p>In mice, only the zygotes and blastomeres from 2-cell embryos are authentic totipotent stem cells (TotiSCs), capable of producing all cell types in both embryonic and extraembryonic tissues and forming an entire organism<sup>1</sup>. However, it remains challenging whether and how TotiSCs, representing the very beginning of a life, can be established <italic>in vitro</italic> in the abs...
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Identifiers and source
- Literature Corpus work
- 78fa23a2-eb71-5ff2-b8c9-dcefb86f50fd
- DOI
- 10.21203/rs.3.pex-1927/v1