Article
Establishment in culture of mouse and human stem cells with expanded fate potential
2018-01-01
Abstract excerpt
The zygote and blastomeres of cleavage stage mouse embryos have the capacity to differentiate to the embryonic and both extra-embryonic lineages and are considered functionally totipotent. Until now, it has not been possible to establish stable cell lines that resemble these totipotent-like cells. In this work, I hypothesised that by modulating signalling pathways known to be important in early embryonic developme...
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Identifiers and source
- Literature Corpus work
- 5f28a32b-4911-5646-947a-c8a3830e4c18
- DOI
- 10.17863/cam.22809