Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced HSC-like cell generation from mouse pluripotent stem cells in a 3D induction system cocultured with stromal cells

19 Jun 2021

Abstract excerpt

Abstract Background Decades of efforts have attempted to differentiate the pluripotent stem cells (PSCs) into truly functional hematopoietic stem cells (HSCs), yet the problems of low differentiation efficiency in vitro and poor hematopoiesis reconstitution in vivo still exist, mainly attributing to the lack of solid, reproduced, or pursued differentiation system. Methods In this study, we established an in vitro...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Pluripotent Stem Cells Research
Share to Zebrafish Biomedical Research Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34147128
DOI: 10.1186/s13287-021-02434-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced HSC-like cell generation from mouse pluripotent stem cells in a 3D induction system cocultured with stromal cellsPMID 34147128Read ↗

Pluripotent Stem Cells: The Last 10 YearsSemantic proximity Read ↗

New trends in cellular therapySemantic proximity Read ↗

Advances in Pluripotent Stem Cells: History, Mechanisms, Technologies, and ApplicationsSemantic proximity Read ↗

Advancements and Innovative Strategies in Induced Pluripotent Stem Cell‐Derived Mesenchymal Stem Cell Therapy: A Comprehensive ReviewSemantic proximity Read ↗

Advantages and challenges of ex vivo generation and expansion of human hematopoietic stem cells from pluripotent stem cellsSemantic proximity Read ↗

Single-cell qPCR facilitates the optimization of hematopoietic differentiation in hPSCs/OP9 coculture system.Semantic proximity Read ↗

Comparative analysis of mesenchymal stem/stromal cells derived from human induced pluripotent stem cells and the cognate umbilical cord mesenchymal stem/stromal cellsSemantic proximity Read ↗

Generation of CD34 <sup>+</sup> CD43 <sup>+</sup> hematopoietic progenitors to induce thymocytes from human pluripotent stem cellsSemantic proximity Read ↗

Generating Functional Cells Through Enhanced Interspecies Chimerism with Human Pluripotent Stem CellsSemantic proximity Read ↗

Generation of complex bone marrow organoids from human induced pluripotent stem cellsSemantic proximity Read ↗

Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D cultureSemantic proximity Read ↗

In Vitro Differentiation of Embryonic and Adult Stem Cells into Hepatocytes: State of the ArtSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.