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Article

International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease.

Pharmacological reviews - 1 Jan 2015

Bryant Clare E, Orr Selinda, Ferguson Brian, Symmons Martyn F, Boyle Joseph P, Monie Tom P

Abstract excerpt

Since the discovery of Toll, in the fruit fly Drosophila melanogaster, as the first described pattern recognition receptor (PRR) in 1996, many families of these receptors have been discovered and characterized. PRRs play critically important roles in pathogen recognition to initiate innate immune responses that ultimately link to the generation of adaptive immunity. Activation of PRRs leads to the induction of...

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Identifiers

PMID: 25829385
DOI: 10.1124/pr.114.009928
PMCID: PMC4394686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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