Article

<i>De novo</i> design of ACE2 protein decoys to neutralize SARS-CoV-2

2020-08-03

Abstract excerpt

There is an urgent need for the ability to rapidly develop effective countermeasures for emerging biological threats, such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes the ongoing coronavirus disease 2019 (COVID-19) pandemic. We have developed a generalized computational design strategy to rapidly engineer de novo proteins that precisely recapitulate the protein surface targeted...

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Literature Corpus work: 78b57a4f-2885-57c2-9b6e-b6bb9f85106e
DOI: 10.1101/2020.08.03.231340

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