Article

A DERIVED RELAXATION CONTRAST FROM SYNTHETIC MRI FOR DETECTING NETWORK MICROSTRUCTURAL VULNERABILITY

2026-04-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Odor identification impairment is an early marker of Alzheimer’s disease (AD) that predicts memory decline, yet its underlying microstructural basis remains unclear. We hypothesized that mild cognitive impairment (MCI) involves early myelin and lipid disruption within olfactory–limbic circuits, detectable using a synthetic MRI–derived contrast that provides complementary sen...

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Literature Corpus work: 521911d8-286f-5496-b301-8ea0d89742a7
DOI: 10.64898/2026.04.08.717271

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