Article

Diffusion-relaxation MRI as virtual histology: separable microstructural signatures of AD pathology in ex vivo human brain

2026-05-25

Abstract excerpt

<title>Abstract</title> <p>Cognitive decline in Alzheimer's disease (AD) reflects progressive disruption of cellular and microstructural organization, yet the biological specificity of conventional MRI signals remains poorly understood. Multidimensional diffusion–relaxation MRI (MD-MRI) resolves sub-voxel tissue heterogeneity and may offer a framework for linking imaging signals to underlying neuropathology. We t...

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Literature Corpus work: 4cd88840-5c90-5e05-9df9-6ffdcdcd0d70
DOI: 10.21203/rs.3.rs-9657671/v1

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