Article

SEC-seq: Association of molecular signatures with antibody secretion in thousands of single human plasma cells

2022-08-26

Abstract excerpt

<h4>ABSTRACT</h4> Protein secretion drives many functions in vivo ; however, methods to link secretions with surface markers and transcriptomes have been lacking. By accumulating secretions close to secreting cells held within cavity-containing hydrogel nanovials, we demonstrate workflows to analyze the amount of IgG secreted from single human antibody-secreting cells and link this information to surface marker...

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Literature Corpus work: 77f04f5a-3268-58b0-b71d-71ad6ea85ff4
DOI: 10.1101/2022.08.25.505190

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