Article

Secretion encoded single-cell sequencing (SEC-seq) uncovers gene expression signatures associated with high VEGF-A secretion in mesenchymal stromal cells

2023-01-08

Abstract excerpt

Cells secrete numerous bioactive molecules essential for the function of healthy organisms. However, there are no scalable methods to link individual cell secretions to their transcriptional state. By developing and using secretion encoded single-cell sequencing (SEC-seq), which exploits hydrogel nanovials to capture individual cells and their secretions, we simultaneously measured the secretion of vascular endoth...

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Literature Corpus work: 4a11f052-247e-5ae3-900f-db2afca1f4e9
DOI: 10.1101/2023.01.07.523110

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