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Multidimensional analysis of matched primary and recurrent glioblastoma identifies Fcγ receptors upregulation on microglia as a contributor of tumor recurrence

2023-04-21

Abstract excerpt

<h4>Background: </h4> : Glioblastoma (GBM) is a lethal brain tumor without effective treatment options. The aim of this study was to characterize longitudinal tumor immune microenvironment (iTME) changes in order to find potential actionable targets to prevent GBM-induced immune evasion mechanisms. <h4>Methods: </h4> : This study included 15 patient-matched treatment-naïve WHO grade 4 primary (pGBM) and recurrent...

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Literature Corpus work
77c77e4f-a69e-5afa-860a-e3a9254e7361
DOI
10.1101/2023.04.21.537308
Open publication

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Multidimensional analysis of matched primary and recurrent glioblastoma identifies Fcγ receptors upregulation on microglia as a contributor of tumor recurrenceDOI 10.1101/2023.04.21.537308
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