Article

Mouse models of hereditary hemochromatosis do not develop early liver fibrosis in response to a high fat diet

2018-05-10

Abstract excerpt

Hepatic iron overload, a hallmark of hereditary hemochromatosis (HH), triggers progressive liver disease. There is also increasing evidence for a pathogenic role of iron in non-alcoholic fatty liver disease (NAFLD), which may progress to non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis and hepatocellular cancer. Mouse models of HH and NAFLD can be used to explore potential interactions between iron and li...

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Literature Corpus work: 77c4f155-d0c6-5d74-beb3-2008d176aea1
DOI: 10.1101/319442

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