Article
The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis.
Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2006
Adams Leon A, Angulo Paul, Abraham Susan C, Torgerson Heidi, Brandhagen David
Abstract excerpt
OBJECTIVES: The variability in phenotypic expression of hereditary hemochromatosis (HH) is not fully understood. We sought to examine whether the metabolic syndrome, hepatic steatosis or steatohepatitis influenced hepatic fibrosis among patients with HH and iron overload. METHODS: We identified 86 patients with C282Y/C282Y or C282Y/H63D HH and iron overload (hepatic iron concentration (HIC) >2,200 microg/g for...
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