Article

Modulation of mutant <i> Kras <sup>G12D</sup> </i> -driven lung tumorigenesis <i>in vivo</i> by gain or loss of PCDH7 function

2018-06-08

Abstract excerpt

<h4>ABSTRACT</h4> PROTOCADHERIN 7 (PCDH7), a transmembrane receptor and member of the Cadherin superfamily, is frequently overexpressed in lung adenocarcinoma and is associated with poor clinical outcome. While PCDH7 was recently shown to promote transformation and facilitate brain metastasis in lung and breast cancers, decreased PCDH7 expression has also been documented in colorectal, gastric, and invasive bladd...

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Literature Corpus work: 7759ff0b-2caa-5278-b041-18150871a865
DOI: 10.1101/343103

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