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Article

SERPINE1: A Molecular Switch in the Proliferation-Migration Dichotomy in Wound-“Activated” Keratinocytes

1 Mar 2014

Abstract excerpt

Significance: A highly interactive serine protease/plasmin/matrix metalloproteinase axis regulates stromal remodeling in the wound microenvironment. Current findings highlight the importance of stringent controls on protease expression and their topographic activities in cell proliferation, migration, and tissue homeostasis. Targeting elements in this cascading network may lead to novel therapeutic approaches for...

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Share to Periodontal Regeneration and Treatments
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Identifiers

PMID: 24669362
DOI: 10.1089/wound.2013.0512

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