Article

Cancer cells communicate with macrophages to prevent T cell activation during development of cell cycle therapy resistance

2022-09-17

Abstract excerpt

Cancer cells evolve, acquire resistance to therapy and change their environment. One resistance mechanism involves altering communication with non-malignant cells in the tumor microenvironment (TME). By corrupting the signals for growth and survival, evolving cancer cells can engineer a pro-tumor TME. However, the specific interactions between malignant and non-malignant cells that predispose drug resistance and t...

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Literature Corpus work: 773a8abb-507f-546a-98cf-d76c2cbf8a54
DOI: 10.1101/2022.09.14.507931

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