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Article

Allies or Enemies—The Multifaceted Role of Myeloid Cells in the Tumor Microenvironment

28 Nov 2019

Abstract excerpt

For decades, cancer was considered a disease driven by genetic mutations in tumor cells, therefore afflicting a single cell type. This simplified view was slowly replaced by the understanding that interactions between malignant cells and neighboring stromal and immune cells-the tumor microenvironment (TME)-profoundly shape cancer progression. This understanding paved the way for an entirely new form of therapy...

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PMID: 31849950
DOI: 10.3389/fimmu.2019.02746

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