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Functional comparisons of the virus sensor RIG-I from humans, the microbat <i>Myotis daubentonii</i> , and the megabat <i>Rousettus aegyptiacus</i> , and their response to SARS-CoV-2 infection

2023-02-11

Abstract excerpt

<h4>ABSTRACT</h4> Bats (order Chiroptera ) are a major reservoir for emerging and re-emerging zoonotic viruses. Their tolerance towards highly pathogenic human viruses led to the hypothesis that bats may possess an especially active antiviral interferon (IFN) system. Here, we cloned and functionally characterized the virus RNA sensor, Retinoic Acid-Inducible Gene-I (RIG-I), from the “microbat” Myotis daubentoni...

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Literature Corpus work
77314570-0851-56c2-9b08-10991e446cf4
DOI
10.1101/2023.02.08.527785
Open publication

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Functional comparisons of the virus sensor RIG-I from humans, the microbat <i>Myotis daubentonii</i> , and the megabat <i>Rousettus aegyptiacus</i> , and their response to SARS-CoV-2 infectionDOI 10.1101/2023.02.08.527785
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