Article

RNA length and receptor usage define innate immune recognition across species

2026-05-21

Abstract excerpt

Recognition of viral double-stranded RNA (dsRNA) is a central trigger of innate antiviral immunity, yet the role of RNA length in shaping immune sensing across species remains poorly defined. Here, we identify RNA length as a key determinant of innate immune activation and demonstrate that this parameter is differentially tuned across vertebrate hosts. Using defined dsRNA molecules, we compared immune responses in...

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Literature Corpus work: 8c17a740-0a5c-56b2-85a8-0a4d78b1bae2
DOI: 10.64898/2026.05.21.726451

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