Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CRISPR-based rapid molecular diagnostic tests for fusion-driven leukemias

8 Jul 2024

Abstract excerpt

ABSTRACT: Fusion oncogenes can be cancer-defining molecular alterations that are essential for diagnosis and therapy selection.1,2 Rapid and accessible molecular diagnostics for fusion-driven leukemias such as acute promyelocytic leukemia (APL), Philadelphia chromosome-positive acute lymphoblastic leukemia, and chronic myeloid leukemia (CML) are unavailable, creating a barrier to timely diagnosis and effective...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Advanced biosensing and bioanalysis techniques
Share to CRISPR and Genetic Engineering

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38976877
DOI: 10.1182/blood.2023022908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CRISPR-based rapid molecular diagnostic tests for fusion-driven leukemiasPMID 38976877Read ↗

Rapid detection of myeloid neoplasm fusions using Single Molecule Long-Read SequencingSemantic proximity Read ↗

RAPID-CRISPR: highly sensitive diagnostic assay for detection of PML::RARA isoforms in acute promyelocytic leukemiaSemantic proximity Read ↗

Ultrarapid Targeted Nanopore Sequencing for Fusion Detection of LeukemiasSemantic proximity Read ↗

CRISPR/Cas12a-Based Ultrasensitive and Rapid Detection of JAK2 V617F Somatic Mutation in Myeloproliferative Neoplasms.Semantic proximity Read ↗

High-Throughput CRISPR Screening in Hematological NeoplasmsSemantic proximity Read ↗

Nucleic acid detection with CRISPR-Cas13a/C2c2.Semantic proximity Read ↗

High-efficiency CRISPR induction of t(9;11) chromosomal translocations and acute leukemias in human blood stem cellsSemantic proximity Read ↗

CRISPR Diagnostics: Advances toward the Point of CareSemantic proximity Read ↗

RAPID: Evaluation of Cas12a Protospacer Nicking and Chimeric Reporters for PAM-independent RNA and DNA diagnosticsSemantic proximity Read ↗

Partial Anchored Capture and Long-Read Sequencing (PACLseq) Enable a Stand-alone Diagnostic Method for Ph-like Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

CRISPR-Cas-amplified urine biomarkers for multiplexed and portable cancer diagnosticsSemantic proximity Read ↗

Advances in next-generation sequencing and emerging technologies for hematologic malignancies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.