Article

Partial Anchored Capture and Long-Read Sequencing (PACLseq) Enable a Stand-alone Diagnostic Method for Ph-like Acute Lymphoblastic Leukemia

2023-08-21

Abstract excerpt

Fusion genes play a crucial role in the development of Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL). Timely and accurate determination of malgenic fusion transcripts that cause Ph-like ALL is essential for guiding treatment decisions. However, due to the complexity of possible gene fusion combination of Ph-like ALL, prevailing molecular diagnostic methods for Ph-like ALL are inefficient...

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Literature Corpus work: d3a3cada-1586-5113-aace-3bbb16c04c7e
DOI: 10.1101/2023.08.19.23294152

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