Article

RNAi epimutations conferring antifungal drug resistance are inheritable

2024-10-16

Abstract excerpt

Epimutations modify gene expression and lead to phenotypic variation while the encoding DNA sequence remains unchanged. Epimutations mediated by RNA interference (RNAi) and/or chromatin modifications can confer antifungal drug resistance and may impact virulence traits in fungi. However, whether these epigenetic modifications can be transmitted across generations following sexual reproduction was unclear. This stu...

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Literature Corpus work: 0ece5deb-ba12-5129-98d6-9c4173bdead2
DOI: 10.1101/2024.10.15.618540

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