Article

Scanning mutagenesis of RNA-binding protein ProQ reveals a quality control role for the Lon protease

2021-07-12

Abstract excerpt

<h4>ABSTRACT</h4> The FinO-domain protein ProQ belongs to a widespread family of RNA-binding proteins (RBPs) involved in gene regulation in bacterial chromosomes and mobile elements. Whilst the cellular RNA targets of ProQ have been established in diverse bacteria, the functionally crucial ProQ residues remain to be identified under physiological conditions. Following our discovery that ProQ deficiency alleviates...

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Literature Corpus work: 76f5a7b1-3ab9-5d4d-9b57-e8bea188cd37
DOI: 10.1101/2021.07.12.452043

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