Article
Interconnection of post-transcriptional regulation: The RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa.
Scientific reports - 27 May 2016
Fernández Lucía, Breidenstein Elena B M, Taylor Patrick K, Bains Manjeet, de la Fuente-Núñez César, Fang Yuan, Foster Leonard J, Hancock Robert E W
Abstract excerpt
Besides being a major opportunistic human pathogen, Pseudomonas aeruginosa can be found in a wide range of environments. This versatility is linked to complex regulation, which is achieved through the action of transcriptional regulators, and post-transcriptional regulation by intracellular proteases including Lon. Indeed, lon mutants in this species show defects in motility, biofilm formation, pathogenicity and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
