Article

Interleukin-11 promotes colonic epithelial repair after mechanical disruption

2026-06-02

Abstract excerpt

The intestinal epithelium relies on rapid repair to maintain homeostasis after injury, and dysregulation of this process contributes to the pathogenesis of inflammatory bowel disease and colorectal cancer. Interleukin-11 (IL-11), a fibroblast-derived cytokine elevated in these diseases, has well-documented effects on stromal cells, but its direct action on intestinal epithelial cells remains poorly characterized....

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Literature Corpus work: 766baa47-9968-5d83-9193-e4aa9da23bb6
DOI: 10.64898/2026.05.29.727830

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