Article

Biofabrication of primary patient tissue-derived inflammatory bowel disease (IBD) model by organoid three-dimensional culture

2025-09-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Inflammatory bowel disease is a chronic gastrointestinal disorder characterized by relapsing inflammation, disruption of the epithelial barrier, and dysregulated immune responses, leading to substantial morbidity. Conventional in vitro cell cultures and animal models often fail to reproduce the cellular heterogeneity, tissue architecture, and patient-specific fe...

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Literature Corpus work: 34a2ca26-b794-5f1c-b128-ec9b3533847c
DOI: 10.21203/rs.3.rs-7498761/v1

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