Article
Centimeter-scale, physiologically relevant intestinal organoids generated entirely from pluripotent stem cells
2024-08-16
Abstract excerpt
Over the past decade, intestinal organoids have shown great promise as a platform to study the development of intestine, elucidate the pathogenesis of diseases such as inflammatory bowel disease (IBD), and model physiological features of intestinal tissue for high-throughput drug screening. However, intestinal organoids derived from adult epithelial stem cells lack cellular diversity, especially those resides in t...
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Identifiers and source
- Literature Corpus work
- a78a6945-f837-5607-b139-e208c94484a4
- DOI
- 10.1101/2024.08.15.608057