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Intestinal organoids in inflammatory bowel disease: advances, applications, and future directions

12 May 2025

Abstract excerpt

Inflammatory bowel disease (IBD), characterized by chronic gastrointestinal inflammation, is a significant global health challenge. Traditional models often fail to accurately reflect human pathophysiology, leading to suboptimal treatments. This review provides an overview of recent advancements in intestinal organoid technology and its role in IBD research. Organoids, derived from patient-specific or pluripotent...

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PMID: 40421006
DOI: 10.3389/fcell.2025.1517121

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