Article

DeepSAP: Improved RNA-Seq Alignment by Integrating Transcriptome Guidance with Transformer-Based Splice Junction Scoring

2025-04-26

Abstract excerpt

Advancements in high-throughput sequencing have revolutionized the field of transcriptomics, pro-viding unprecedented insights into gene expression, splicing events, and fusions. Despite these advancements, the analysis of RNA-seq data remains challenging due to the presence of complex splice junctions, multi-mapped reads, and chimeric events. In this study, we present DeepSAP, an innovative approach that improves...

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Literature Corpus work: 7641227e-6740-5735-bcc0-beed301aa269
DOI: 10.1101/2025.04.23.650072

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