Article

novoRNABreak: local assembly for novel splice junction and fusion transcript detection from RNA-seq data

2022-12-19

Abstract excerpt

<h4>ABSTRACT</h4> We present novoRNABreak, a unified framework for cancer specific novel splice junction and fusion transcript detection in RNA-seq data obtained from human cancer samples. novoRNABreak is based on a local assembly model, which offers a tradeoff between the alignment-based and de novo whole transcriptome assembly (WTA) approaches, namely, being more sensitive in assembling novel junctions that can...

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Literature Corpus work: ad88a989-1af5-58c6-a5b2-7f7cc91951b2
DOI: 10.1101/2022.12.16.520791

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