Article

Analyzing the Performance of Deep Learning Splice Prediction Algorithms

2025-11-20

Abstract excerpt

SpliceAI has become the leading computational tool for predicting splice-altering variants, but restrictive licensing has limited its adoption by commercial clinical laboratories. While open-source reimplementations have emerged with author-reported comparisons, independent benchmarking across diverse datasets is needed to establish their practical equivalence. We compared the original SpliceAI algorithm against t...

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Literature Corpus work: 56cd2d17-805c-5a53-acf8-032c84b77934
DOI: 10.1101/2025.11.20.689501

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