UniSplicer: A deep-learning framework for accurate splice-site prediction and splice-altering mutation detection across diverse taxa.

Abstract excerpt

RNA splicing removes non-coding introns from pre-mRNA to generate mature mRNA in eukaryotes, and accurate identification of splice sites is essential for understanding gene structure and regulation. Traditional gene annotation and splice-site prediction rely heavily on high-quality genome assemblies, extensive functional characterization, and substantial computational and experimental resources, limiting their...

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