Article

Splam: a deep-learning-based splice site predictor that improves spliced alignments

2023-07-29

Abstract excerpt

The process of splicing messenger RNA to remove introns plays a central role in creating genes and gene variants. Here we describe Splam, a novel method for predicting splice junctions in DNA based on deep residual convolutional neural networks. Unlike some previous models, Splam looks at a relatively limited window of 400 base pairs flanking each splice site, motivated by the observation that the biological proce...

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Literature Corpus work: 7b8a08f3-dc53-565b-bdfa-5ac496dc797b
DOI: 10.1101/2023.07.27.550754

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