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Article

In-depth Analysis of the Sirtuin 5-regulated Mouse Brain Acylome using Library-free Data-Independent Acquisitions

2022-08-06

Abstract excerpt

Post-translational modifications (PTMs) dynamically regulate proteins and biological pathways, typically through the combined effects of multiple PTMs. Lysine residues are targeted for various PTMs, including malonylation and succinylation. However, PTMs offer specific challenges to mass spectrometry-based proteomics during data acquisition and processing. Thus, novel and innovative workflows using data-independen...

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Literature Corpus work
762012e0-f398-5da6-8d5f-f8f03224b5ae
DOI
10.1101/2022.08.06.503046
Open publication

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