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Article

Dynamics of Mitochondrial Proteome and Acetylome in Glioblastoma Cells with Contrasting Metabolic Phenotypes.

International journal of molecular sciences - 19 Mar 2024

Fernández-Coto Diana Lashidua, Gil Jeovanis, Ayala Guadalupe, Encarnación-Guevara Sergio

Abstract excerpt

Glioblastoma, a type of cancer affecting the central nervous system, is characterized by its poor prognosis and the dynamic alteration of its metabolic phenotype to fuel development and progression. Critical to cellular metabolism, mitochondria play a pivotal role, where the acetylation of lysine residues on mitochondrial enzymes emerges as a crucial regulatory mechanism of protein function. This...

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Identifiers

PMID: 38542426
DOI: 10.3390/ijms25063450
PMCID: PMC10971019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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