Article

Associations between mosaic loss and schizophrenia or bipolar disorder of young onset

2025-06-16

Abstract excerpt

<h4>ABSTRACT</h4> Mosaic chromosomal alterations (mCAs) accumulate in the brain tissues and are associated with psychiatric disorders. The association between mCAs in circulating blood and schizophrenia (SCZ) and bipolar disorders (BD) has not been fully evaluated. We detected mCAs from blood samples in 2,470 SCZ, 3,732 BD, and 177,773 control subjects. The associations between mCAs and SCZ or BD were evaluated us...

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Literature Corpus work: 760bdca1-d70f-54da-aaee-d57d4e3d433e
DOI: 10.1101/2025.06.13.25329510

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