Article
Genome-wide analysis of DNA methylation in 106 schizophrenia family trios in Han Chinese.
EBioMedicine - 1 Oct 2021
Shen Lu, Lv Xiaoying, Huang Hailiang, Li Mo, Huai Cong, Wu Xi, Wu Hao, Ma Jingsong, Chen Luan, Wang Ting, Tan Jie, Sun Yidan, Li Lixing, Shi Yi, Yang Chao, Cai Lei, Lu Yana, Zhang Yan, Weng Saizheng, Tai Shaobin, Zhang Na, He Lin, Wan Chunling, Qin Shengying
Abstract excerpt
BACKGROUND: Schizophrenia (SCZ) is a severe psychiatric disorder that affects approximately 0.75% of the global population. Both genetic and environmental factors contribute to development of SCZ. SCZ tends to run in family while both genetic and environmental factor contribute to its etiology. Much evidence suggested that alterations in DNA methylations occurred in SCZ patients. METHODS: To investigate potential...
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