Article
Simulations reveal high efficiency and confinement of a population suppression CRISPR toxin-antidote gene drive
2022-11-01
Abstract excerpt
Though engineered gene drives hold great promise for spreading through and eventually suppressing populations of disease vectors or invasive species, complications such as resistance alleles and spatial population structure can prevent their success. Additionally, most forms of suppression drives, such as homing drives or driving Y chromosomes, will generally spread uncontrollably between populations with even sma...
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Identifiers and source
- Literature Corpus work
- 75c758fe-7842-510c-b89d-110bf248bfba
- DOI
- 10.1101/2022.10.30.514459